bionits.blogg.se - Proton charge

#Proton charge windows

Journal of the American Society for Mass Spectrometry 2021, 32 Denaturing and Native Mass Spectrometric Analytics for Biotherapeutic Drug Discovery Research: Historical, Current, and Future Personal Perspectives. Multiple Roles of SARS-CoV-2 N Protein Facilitated by Proteoform-Specific Interactions with RNA, Host Proteins, and Convalescent Antibodies. Sequential Ion–Ion Reactions for Enhanced Gas-Phase Sequencing of Large Intact Proteins in a Tribrid Orbitrap Mass Spectrometer. Quantitative Top-Down Proteomics by Isobaric Labeling with Thiol-Directed Tandem Mass Tags.

Konrad Winkels, Tomas Koudelka, Andreas Tholey.

Online μSEC2-nRPLC-MS for Improved Sensitivity of Intact Protein Detection of IEF-Separated Nonhuman Primate Cerebrospinal Fluid Proteins. Cline, Carina Alvarez, Jiana Duan, Steven M. Journal of the American Society for Mass Spectrometry 2022, 33 Improving the Center Section Sequence Coverage of Large Proteins Using Stepped-Fragment Ion Protection Ultraviolet Photodissociation. Enhanced Top-Down Protein Characterization with Electron Capture Dissociation and Cyclic Ion Mobility Spectrometry. Ion–Ion Charge Reduction Addresses Multiple Challenges Common to Denaturing Intact Mass Analysis. Bailey, Romain Huguet, Christopher Mullen, John E.

#Proton charge windows

Characterization of Homopolymer Distributions via Direct Infusion ESI-MS/MS using Wide Mass-to-Charge Windows and Gas-Phase Ion/Ion Reactions. Online Hydrophilic Interaction Chromatography (HILIC) Enhanced Top-Down Mass Spectrometry Characterization of the SARS-CoV-2 Spike Receptor-Binding Domain. Wilson, Aivett Bilbao, Juan Wang, Yen-Chen Liao, Dusan Velickovic, Roza Wojcik, Marta Passamonti, Rui Zhao, Andrea F. Ethane-Bridged Hybrid Monolithic Column with Large Mesopores for Boosting Top-Down Proteomic Analysis. Chao Wang, Yu Liang, Baofeng Zhao, Zhen Liang, Lihua Zhang, Yukui Zhang.Approaches to Heterogeneity in Native Mass Spectrometry. Top-Down Identification and Sequence Analysis of Small Membrane Proteins Using MALDI-MS/MS. Jakob Meier-Credo, Laura Preiss, Imke Wüllenweber, Anja Resemann, Christoph Nordmann, Jure Zabret, Detlev Suckau, Hartmut Michel, Marc M.Validation of Top-Down Proteomics Data by Bottom-Up-Based N-Terminomics Reveals Pitfalls in Top-Down-Based Terminomics Workflows. Kaulich, Matthias Leippe, Andreas Tholey. Konrad Winkels, Tomas Koudelka, Philipp T.Improving Accuracy in Mass Spectrometry-Based Mass Determination of Intact Heterogeneous Protein Utilizing the Universal Benefits of Charge Reduction and Alternative Gas-Phase Reactions. Qingrong Chen, Rongrong Dai, Xiaopeng Yao, Lingxiao Chaihu, Wenjun Tong, Yanyi Huang, Guanbo Wang.Impact of Internal Fragments on Top-Down Analysis of Intact Proteins by 193 nm UVPD. Dunham, Benqian Wei, Carter Lantz, Joseph A. This article is cited by 30 publications.

Despite the recent technological advances in Fourier transform mass spectrometry (FTMS) instrumentation, top-down proteomics (TDP) is currently mostly applied to the characterization of proteoforms 30 kDa identified on the liquid chromatography time scale.